#  Mohammad Rashidian 

Assistant Professor of Radiology

 

 

 



   ![Mohammad Rashidian ](/sites/g/files/omnuum13191/files/styles/hwp_4_5__320x400/public/2026-09/Rashidian%2C%20Mohammad_0.jpg?itok=B-3c4D-s) 

 



 

 email [Mohammad\_Rashidian@dfci.harvard.edu](mailto:Mohammad_Rashidian@dfci.harvard.edu) 

 laptop\_windows [Lab Website](https://labs.dana-farber.org/rashidianlab/) 

 laptop\_windows [Publications](https://scholar.google.com/citations?user=zb6KNZcAAAAJ&hl=en) 

 

 



 

Immunotherapy has transformed cancer treatment, yet many patients still do not achieve effective responses. In our lab, we explore cancer immunology through a multidisciplinary approach that integrates chemical biology, protein engineering, molecular biology, and immunology. We investigate how cancer immunotherapies impact the tumor microenvironment and aim to develop innovative diagnostic, prognostic, and therapeutic tools for precise cancer detection, characterization, treatment, and prevention.

A key focus of our research is enhancing the activity and persistence of CAR T cells. Although CAR T cells have revolutionized the treatment of various blood cancers, their effectiveness often diminishes over time, leading to patient relapse. To address this, we are developing novel immunotherapeutics designed to guide CAR T cells toward a memory phenotype, potentially prolonging treatment efficacy and reducing relapse rates.

We are also leveraging protein engineering to develop novel imaging probes for detecting inflammation and early-stage cancer, as well as inflammatory-mediated diseases. Additionally, our work includes applying protein engineering to create precision therapeutics for autoimmune diseases, aiming to deliver targeted and effective treatments.



 

 

 





 

 

- ## Person Categories
    
     [Faculty](/person-categories/faculty)
- ## Research Area
    
     [Cancer biology](/research-area/cancer-biology) [Immunology and inflammation](/research-area/immunology-and-inflammation) [Protein function, modifications, and regulation](/research-area/protein-function-modifications-and-regulation) [Synthetic biology / bioengineering](/research-area/synthetic-biology-bioengineering)