#  Tim Springer 

Latham Family Professor of Biological Chemistry and Molecular Pharmacology

 

 

 



   ![tim springer](/sites/g/files/omnuum13191/files/styles/hwp_4_5__320x400/public/2026-09/springer-profile_1.jpg?itok=EUbitP9Y) 

 



 

 email [springer\_lab@crystal.harvard.edu](mailto:springer_lab@crystal.harvard.edu) 

 laptop\_windows [Lab Website](https://timothyspringer.org/) 

 laptop\_windows [Publications](https://timothyspringer.org/publications) 

 

 



 

My lab studies receptor-ligand interactions and signal transmission across membranes. We use a wide range of structural, cell biological, and single molecule techniques to answer important questions relevant to immunology, hemostasis, mammalian biology, and human disease. A common theme throughout our research is how force interacts with protein conformational change to activate integrins, von Willebrand factor, proteins of the transforming growth factor-beta family, and adhesins on malaria sporozoites.



 

 

 





 

 

- ## Person Categories
    
     [Faculty](/person-categories/faculty)
- ## Research Area
    
     [Biophysics](/research-area/biophysics) [Cancer biology](/research-area/cancer-biology) [Protein function, modifications, and regulation](/research-area/protein-function-modifications-and-regulation) [Receptors and signaling](/research-area/receptors-and-signaling) [Synthetic biology / bioengineering](/research-area/synthetic-biology-bioengineering)