Vladimir Denic
Professor of Molecular and Cellular Biology
Harvard University NorthWest Building, Room 445.30 52 Oxford Street Boston, MA 02115
The Denic lab takes advantage of novel methodologies for studying large-scale genetic interactions in budding yeast as well as mass spectrometry-based characterization of natively-isolated protein complexes in order to identify the essential components required for several membrane-associated cellular processes. We then carry out targeted and systematic biochemical reconstitution strategies using the identified components in order to go from parts lists to functional and mechanistic insights.